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Introducing the ADS1299 4-channel analog front-end (AFE) for biopotential measurement systems. This high-performance AFE is designed to provide accurate and reliable data acquisition for a wide range of biopotential measurements, including electrocardiography (ECG) and electromyography (EMG). The ADS1299 offers low-noise, high-resolution A/D conversion with a flexible input multiplexer, enabling simultaneous measurement of multiple biopotential signals. Its integrated lead-off detection feature helps ensure measurement accuracy by identifying when electrodes become disconnected or when skin impedance changes. With its programmable gain amplifiers and digital filtering capabilities, the ADS1299 is adaptable to a variety of measurement needs and signal conditions. Additionally, its low power consumption and small form factor make it an ideal choice for portable and wearable biopotential monitoring devices. Overall, the ADS1299 AFE is an excellent solution for biopotential measurement applications, offering superior performance and flexibility to meet the demands of today's healthcare and consumer wellness markets.